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February 14, 2003

Live a long time?

Discovering a Secret of Long Life (a gene even). For the record, my maternal grandfather lived until 100 and his aunt lived until 115. {actually not relevant, since the article is about mitochondria-so now you know my secret, I don't read everything I link....}

Posted by razib at 10:17 AM

Except the mitochondrial DNA is inherited through your mother, her mother, etc.

(my maternal grandma, still goin strong with no health problems at 85, her sister is still healthy at 94 and their mom lived to be 99)


Posted by: David at February 14, 2003 11:10 AM

didn't even have time to read the article....

but my mom's mom is 85.

Posted by: razib at February 14, 2003 12:50 PM

I'm a layman when it comes to DNA and I have a queston. Since your grandfather donates an X chromosome to your mother, wouldn't he also transmit his maternal mitochondrial DNA to your mother?

Someone please clarify this process for me.

Posted by: the alpha male at February 14, 2003 03:11 PM

mitocondria come via the egg-from the mother. that is why mitochondrial DNA is always the mother lineage. mtDNA is separate from nuclear DNA. this hints to the idea that mitochondria were originally independent organisms.

Posted by: razib at February 14, 2003 03:45 PM

Thanks - i didn't know that.

Posted by: the alpha male at February 14, 2003 05:37 PM

Razib, if your grandfather was related to his aunt via a woman (ie, if the aunt was his mother's sister), then the two of them had the same mitochondrial genes. If, however, the aunt was his *father's* sister, then no dice. Either way, *you* don't have the same mitochondria unless you got them somewhere else (say, if your grandfather married his sister).

Posted by: beth at February 15, 2003 11:39 PM

yeah beth-i know. didn't read the article before i posted the anecdote. either way-sux 2 be me :)

Posted by: razib at February 16, 2003 01:45 AM