A lot of the time I focus on stuff that interest's me-population histories and palaeoanthropology-but science does have human consequences. So, here is an article that focuses on the targetting of a gene that seems to be implicated in a serious neurological disorder. Read the fine print and you note only 3,000 children are affected nationally (the United States). But-3,000 here, 10,000 there, and pretty soon a medical revolution is on your hands.