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October 10, 2004

HIV resistance

Some reference has been made to possible resistance to HIV among a subset of humans. Here is the full text of the paper Evaluating plague and smallpox as historical selective pressures for the CCR5-{Delta}32 HIV-resistance allele:


...HIV has not infected humans long enough to account for the selective rise of this resistance allele, the frequency of which is estimated at an average of ~10% in European populations (4, 12, 15-18). The allele is virtually absent in African, Asian, Middle Eastern, and American Indian populations....

Posted by razib at 12:25 AM