Substack cometh, and lo it is good. (Pricing)

How science is done

A follow up on the Ancient Archaic Admixture Into the Andamanese story, No evidence for unknown archaic ancestry in South Asia:

Genomic studies have documented a contribution of archaic Neanderthals and Denisovans to non-Africans. Recently, Mondal et al. 2016 (Nature Genetics, doi:10.1038/ng.3621) published a major dataset–the largest whole genome sequencing study of diverse South Asians to date–including 60 mainland groups and 10 indigenous Andamanese. They reported analyses claiming that nearly all South Asians harbor ancestry from an unknown archaic human population that is neither Neanderthal nor Denisovan. However, the statistics cited in support of this conclusion do not replicate in other data sets, and in fact contradict the conclusion.

Last I heard they hadn’t released the bam files. Mistakes are made, that’s how science is done, and other people help in the process of correction. But, it is starting to get worrisome to me to see papers with bioinformatic errors being published in high impact journals.

Posted in Uncategorized

Comments are closed.