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	<title>Comments on: How to build a black dog</title>
	<atom:link href="http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/</link>
	<description>Genetics</description>
	<lastBuildDate>Tue, 03 Apr 2018 05:20:42 +0000</lastBuildDate>
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		<title>By: windy</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12284</link>
		<dc:creator><![CDATA[windy]]></dc:creator>
		<pubDate>Thu, 25 Oct 2007 17:41:34 +0000</pubDate>
		<guid isPermaLink="false">#comment-12284</guid>
		<description><![CDATA[&lt;i&gt;So it should be a no-brainer to breed, say, a red poodle.&lt;/i&gt;&#160;&lt;br&gt;&#160;&lt;br&gt;You&#039;re late - see Google :)&#160;&lt;br&gt;&#160;&lt;br&gt;As for how much people would pay, not every single breed is &quot;available&quot; in black, but I can&#039;t think of any body type of dog where there&#039;s a glaring lack of black options. The most dramatic things would be something like a black Irish setter - meh. To be able to have a different-colour clone of &lt;i&gt;your&lt;/i&gt; dog would be something else. Or how about a dog coloured like a silver fox or an African wild dog?]]></description>
		<content:encoded><![CDATA[<p><i>So it should be a no-brainer to breed, say, a red poodle.</i>&nbsp;<br />&nbsp;<br />You&#8217;re late &#8211; see Google :)&nbsp;<br />&nbsp;<br />As for how much people would pay, not every single breed is &#8220;available&#8221; in black, but I can&#8217;t think of any body type of dog where there&#8217;s a glaring lack of black options. The most dramatic things would be something like a black Irish setter &#8211; meh. To be able to have a different-colour clone of <i>your</i> dog would be something else. Or how about a dog coloured like a silver fox or an African wild dog?</p>
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	<item>
		<title>By: p-ter</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12285</link>
		<dc:creator><![CDATA[p-ter]]></dc:creator>
		<pubDate>Thu, 25 Oct 2007 16:57:05 +0000</pubDate>
		<guid isPermaLink="false">#comment-12285</guid>
		<description><![CDATA[hm, I don&#039;t know that the reason for a white coat is fully known. If it&#039;s downstream of mc1r (ie. if it&#039;s a loss of function in some protein necessary for transporting melanin to the skin, like in some forms of albinism), you&#039;d have to get a functioning version of that gene, then the relevant mc1r allele. once the genes are known, then it should be a pretty easy breeding scheme (or, if germ-line engineering in the dog takes off, a few years of playing around).]]></description>
		<content:encoded><![CDATA[<p>hm, I don&#8217;t know that the reason for a white coat is fully known. If it&#8217;s downstream of mc1r (ie. if it&#8217;s a loss of function in some protein necessary for transporting melanin to the skin, like in some forms of albinism), you&#8217;d have to get a functioning version of that gene, then the relevant mc1r allele. once the genes are known, then it should be a pretty easy breeding scheme (or, if germ-line engineering in the dog takes off, a few years of playing around).</p>
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		<title>By: David Boxenhorn</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12286</link>
		<dc:creator><![CDATA[David Boxenhorn]]></dc:creator>
		<pubDate>Thu, 25 Oct 2007 16:26:42 +0000</pubDate>
		<guid isPermaLink="false">#comment-12286</guid>
		<description><![CDATA[Thanks, p-ter.&#160;&lt;br&gt;&#160;&lt;br&gt;So it should be a no-brainer to breed, say, a red poodle.]]></description>
		<content:encoded><![CDATA[<p>Thanks, p-ter.&nbsp;<br />&nbsp;<br />So it should be a no-brainer to breed, say, a red poodle.</p>
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	<item>
		<title>By: p-ter</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12287</link>
		<dc:creator><![CDATA[p-ter]]></dc:creator>
		<pubDate>Thu, 25 Oct 2007 16:10:20 +0000</pubDate>
		<guid isPermaLink="false">#comment-12287</guid>
		<description><![CDATA[yep&#160;&lt;br&gt;&#160;&lt;br&gt;&lt;a href=&quot;http://www.springerlink.com/content/kr1bj48lv4t2ywdx/&quot;&gt;http://www.springerlink.com/content/kr1bj48lv4t2ywdx/&lt;/a&gt;]]></description>
		<content:encoded><![CDATA[<p>yep&nbsp;<br />&nbsp;<br /><a href="http://www.springerlink.com/content/kr1bj48lv4t2ywdx/">http://www.springerlink.com/content/kr1bj48lv4t2ywdx/</a></p>
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	<item>
		<title>By: David Boxenhorn</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12288</link>
		<dc:creator><![CDATA[David Boxenhorn]]></dc:creator>
		<pubDate>Thu, 25 Oct 2007 15:58:56 +0000</pubDate>
		<guid isPermaLink="false">#comment-12288</guid>
		<description><![CDATA[How about &lt;a href=&quot;http://images.google.com/images?q=golden+retriever&quot;&gt;red dogs&lt;/a&gt;? MC1R?]]></description>
		<content:encoded><![CDATA[<p>How about <a href="http://images.google.com/images?q=golden+retriever">red dogs</a>? MC1R?</p>
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	<item>
		<title>By: bbartlog</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12289</link>
		<dc:creator><![CDATA[bbartlog]]></dc:creator>
		<pubDate>Thu, 25 Oct 2007 09:54:18 +0000</pubDate>
		<guid isPermaLink="false">#comment-12289</guid>
		<description><![CDATA[MC1R is also expressed in the brain (at least in humans), resulting in differences in pain sensitivity and perhaps temperament. Is this ligand/defen&lt;wbr&gt;sin/what-have-you also found in the brain? Would the binding there have effects beyond coat color? I would assume so. There&#039;s a FAQ for Labrador Retriever coat color which dismisses the supposed folk wisdom that Black Labs are better hunters, but it sounds like the folk wisdom might be right.]]></description>
		<content:encoded><![CDATA[<p>MC1R is also expressed in the brain (at least in humans), resulting in differences in pain sensitivity and perhaps temperament. Is this ligand/defen<wbr>sin/what-have-you also found in the brain? Would the binding there have effects beyond coat color? I would assume so. There&#8217;s a FAQ for Labrador Retriever coat color which dismisses the supposed folk wisdom that Black Labs are better hunters, but it sounds like the folk wisdom might be right.</wbr></p>
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	<item>
		<title>By: p-ter</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12290</link>
		<dc:creator><![CDATA[p-ter]]></dc:creator>
		<pubDate>Wed, 24 Oct 2007 21:03:37 +0000</pubDate>
		<guid isPermaLink="false">#comment-12290</guid>
		<description><![CDATA[&lt;i&gt;Isn&#039;t the dog an atypical species?&lt;/i&gt;&#160;&lt;br&gt;&#160;&lt;br&gt;ha. yeah, probably :)]]></description>
		<content:encoded><![CDATA[<p><i>Isn&#8217;t the dog an atypical species?</i>&nbsp;<br />&nbsp;<br />ha. yeah, probably :)</p>
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	<item>
		<title>By: razib</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12291</link>
		<dc:creator><![CDATA[razib]]></dc:creator>
		<pubDate>Wed, 24 Oct 2007 19:54:46 +0000</pubDate>
		<guid isPermaLink="false">#comment-12291</guid>
		<description><![CDATA[not in terms of coat pattern genetics.]]></description>
		<content:encoded><![CDATA[<p>not in terms of coat pattern genetics.</p>
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	<item>
		<title>By: ziel</title>
		<link>http://www.gnxp.com/new/2007/10/24/how-to-build-a-black-dog/#comment-12292</link>
		<dc:creator><![CDATA[ziel]]></dc:creator>
		<pubDate>Wed, 24 Oct 2007 19:25:36 +0000</pubDate>
		<guid isPermaLink="false">#comment-12292</guid>
		<description><![CDATA[Isn&#039;t the dog an atypical species?]]></description>
		<content:encoded><![CDATA[<p>Isn&#8217;t the dog an atypical species?</p>
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