Ancient and Recent Positive Selection Transformed Opioid cis-Regulation in Humans: …In addition, the pattern of linked nucleotide and microsatellite variation among and within modern human populations suggests that recent selection, subsequent to the fixation of the human-specific mutations and the peopling of the globe, has favored different prodynorphin cis-regulatory alleles in different parts of the … Continue reading Ancient and Recent Positive Selection Transformed Opioid cis-Regulation in Humans