ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. ScienceDaily has a summary:
Asthma researchers have found that a gene variant known to raise the risk of childhood asthma in European children plays a similar role in white American children, but not in African American children.
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Researchers from The Children’s Hospital of Philadelphia found that variants in the ORMDL3 gene were associated with childhood-onset asthma among U.S. patients of European ancestry. In 2007 a study team based in Europe had identified the ORMDL3 gene, located on chromosome 17, as contributing to childhood asthma among British and German children.