Tuesday, August 12, 2008

Fear and living with dopamine....   posted by Razib @ 8/12/2008 06:08:00 PM

Another dopamine-related fear and anxiety related gene, COMT Genetic Variation Affects Fear Processing: Psychophysiological Evidence. ScienceDaily with the predigested form. Quick points,

1) It looks like the SNP in question does show some variation world wide. Europeans seem to have a higher frequency of the MET/MET genotype than Africans, while Asians tend to be lowest.

2) I notice that some genes around this locus show up as being under selection in Haplotter. Within +/- 1.5 megabases.

3) This locus is implicated in a lot of other stuff.

4) Genetic Future's post The challenge of psychiatric genetics is probably worth a read if you are interested in these findings.

I don't have much original to say here that I/we haven't said before. So I invite you to browse the links below....

Related: Optimal personality and way of life, Really ancient morphs?, DRD4, politics & friendship, Heritability of the Ultimatum Game, DRD4, sex and Jews, More DRD4, ADHD & DRD4 and Picking apart the black box.