Substack cometh, and lo it is good. (Pricing)

Happy DNA Day (and whole genome sequencing yourself)

Today is “DNA Day,” I checked Nebula Genomics website to see if there was a deal. So I got the 30x whole genome sequencing for $199+$24.99/month subscription. The deal is you have to get the subscription, but you can cancel at any time. What I plan to do is just download my data when the results come back and the subscription starts ticking, and cancel after that. The other options are more expensive. But, they won’t let you add more than 1 item unless you get the most expensive upfront deal, so what I did was just started separate carts and sent the order to separate email addresses.

And yes, I have my own DNA sequenced. This is for friends and family.

If you want to download my whole genome sequence, from raw reads to bam files to vcf’s, go here.

Update: It was pointed out to me that quarterly would charge $75 as it will be $25 per month quarterly (3 months).

6 thoughts on “Happy DNA Day (and whole genome sequencing yourself)

  1. Razib,

    Under what, if any, circumstances would you every recommend deeper coverage? 50x or 100x? I ask because I have a relative who passed away suddenly and without warning. We managed to get some DNA from the body and are interested in seeing if there SNPs or indels that might have lead to his demise.

    BTW you popped up as “Razib from Austin” on the Nebula website.

  2. Subscription pricing on Nebula is quarterly at minimum, so $75, for $274 total. But this is still considerably cheaper than the alternatives (e.g. sequencing.com at $399).

    I picked up a 30x. If you do need deeper coverage there’s no reason to buy the 100x, which is priced disproportionately expensively. You can order two 30x sequences and combine them manually to make your own 60x.

  3. Elon bought Twitter. Lots of wailing and gnashing of teeth from the left and cheering from the right but I don’t think there will be any changes. No way the American regime would allow their communication platform of choice to be bought by a potential enemy unless he agreed to their demands.

  4. If I wanted to do this and give myself something akin to the 23andme treatment, without the privacy risk, how accessible is it for the layman to place themselves on PCA charts and examine for disease-relevant SNP’s?

  5. I am very satisfied with my Nebula purchase. It provided me the most comprehensive raw data file. Far more SNPs than the 23andme V5 raw data, with noticeably different, and more accurate results in calculators.

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